{
  "id": 1737348,
  "title": "Spindle scaling promotes adaptation to polyploidy",
  "url": "https://urgent.news/2026/08/18/spindle-scaling-promotes-adaptation-to-polyploidy",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-18T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.17.745319v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "How the cell division machinery adapts to increases in genome copy number (ploidy) remains an open question with implications for evolution and cancer. Using Xenopus egg extracts and species spanning 2N to 12N ploidy, we found that stepwise increases in ploidy drove spindle multipolarity, accompanied by larger spindles, increased microtubule density, and differential scaling of spindle assembly…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}