{
  "id": 17331923,
  "title": "PatHoST: weakly supervised reconstruction of pathogen spatial distributions from host transcriptomes",
  "url": "https://urgent.news/2026/10/30/pathost-weakly-supervised-reconstruction-of-pathogen-spatial",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-30T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.26.759336v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Dual host-pathogen spatial transcriptomics enables spatially resolved investigation of infection, yet the completeness of pathogen detection remains poorly characterized. Here, we generated pathogen-only spatial transcriptomic sections from a chronic Mycobacterium abscessus lung infection model to experimentally benchmark pathogen detection, revealing substantially increased pathogen transcript…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}