{
  "id": 17250329,
  "title": "One lysine, two acyl marks: 2-hydroxyisobutyrylation and acetylation of G6PD differ in outcome and regulation",
  "url": "https://urgent.news/2026/10/30/one-lysine-two-acyl-marks-2-hydroxyisobutyrylation-and-acetylation-of",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-30T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.29.762733v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Lysine 2-hydroxyisobutyrylation is a widespread post-translational modification enriched in enzymes of central carbon metabolism, yet its site-specific biochemical consequences remain poorly defined and usually inferred from amino acid substitutions or heterogeneously modified protein preparations. Using genetic code expansion technology, we generated homogeneous human glucose-6-phosphate…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}