{
  "id": 16913713,
  "title": "Mindfulness-based therapy may reshape brain responses to opioid cues during addiction treatment",
  "url": "https://urgent.news/2026/10/28/mindfulness-based-therapy-may-reshape-brain-responses-to-opioid-cues",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-28T15:01:50.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-10-mindfulness-based-therapy-reshape-brain.html"
  },
  "original_language": "en",
  "account": null,
  "summary": "A randomized clinical trial conducted by researchers at the Icahn School of Medicine at Mount Sinai has found that Mindfulness-Oriented Recovery Enhancement (MORE), a behavioral therapy used alongside medication treatment, may help individuals with opioid use disorder respond differently to drug-related cues and natural rewards. The study, published in JAMA Psychiatry, utilized brain imaging to examine the effects of MORE on the prefrontal cortex, which plays a crucial role in regulating behavior, decision-making, and reward evaluation. After eight weeks, participants who received MORE demonstrated changes in brain activity associated with reduced cravings and improved abstinence rates compared to those receiving a comparison therapy. MORE combines mindfulness training, cognitive reappraisal, and savoring to reduce the influence of drug-related cues while strengthening responses to natural rewards. The findings suggest that prefrontal function in addiction is not fixed, and recovery of brain function is possible through behavioral treatments.",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}