{
  "id": 16912100,
  "title": "Gnotobiotic OMM12 mice support sustained Clostridioides difficile colonization without antibiotic pretreatment",
  "url": "https://urgent.news/2026/10/28/gnotobiotic-omm12-mice-support-sustained-clostridioides-difficile",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-28T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.27.762127v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Antibiotic-induced disruption of the intestinal microbiota predispose individuals to Clostridioides difficile infection (CDI). Although several animal models reproduce acute CDI, sustained colonization in the presence of a defined resident microbiota remains challenging to study. Here, we show that gnotobiotic OMM12 mice support sustained colonization for at least 20 days following oral challenge…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}