{
  "id": 16769378,
  "title": "Vitamin Derivative Pantethine Alleviates Psoriasis Symptoms in Small Human Trial",
  "url": "https://urgent.news/2026/10/27/vitamin-derivative-pantethine-alleviates-psoriasis-symptoms-in-small",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-27T17:02:30.000Z",
  "source": {
    "name": "GEN Biotechnology",
    "slug": "gen-biotechnology",
    "url": "https://www.genengnews.com/topics/drug-discovery/vitamin-derivative-pantethine-alleviates-psoriasis-symptoms-in-small-human-trial/"
  },
  "original_language": "en",
  "account": "A team of researchers from the State Key Laboratory of Biomedical Analysis in Beijing has discovered that the vitamin B5 derivative pantethine may help alleviate symptoms of psoriasis by limiting the activity of dendritic cells (DCs), immune cells linked to autoimmune diseases. In a small human trial, patients with psoriasis who took pantethine alongside topical treatments experienced improved symptoms, particularly those with higher initial blood cholesterol levels. The study, published in the Journal of Experimental Medicine, suggests that metabolic pathways and their associated metabolites, like pantethine, could be promising targets for treating various autoimmune diseases, including psoriasis.",
  "summary": "Researchers found that the vitamin B5 derivative pantethine prevented the development of psoriasis in mice, and in a small-scale trial in human psoriasis patients administering pantethine in combination with topical calcipotriol/betamethasone dipropionate helped to alleviate symptoms. The post Vitamin Derivative Pantethine Alleviates Psoriasis Symptoms in Small Human Trial appeared first on GEN -…",
  "key_points": [
    "Pantethine vitamin derivative studied for psoriasis treatment",
    "Small human trial shows symptom alleviation in patients",
    "Improved outcomes linked to higher initial cholesterol levels"
  ],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}