{
  "id": 16558287,
  "title": "Cross-Tissue Concordance of Blood-Trained Protein EpiScores in Donor-Matched GTEx Tissues",
  "url": "https://urgent.news/2026/10/25/cross-tissue-concordance-of-blood-trained-protein-episcores-in-donor",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-25T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.20.760574v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Background: Protein EpiScores are DNA methylation (DNAm)-derived predictors of circulating protein levels that may provide accessible biomarkers of disease-related molecular variation. However, because these models were developed in blood, it remains unclear whether they preserve interindividual variation when applied to other tissues. We evaluated the cross-tissue concordance of blood-trained…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}