{
  "id": 163709,
  "title": "Pro-inflammatory microglia drive escalated alcohol consumption during early abstinence",
  "url": "https://urgent.news/2026/08/04/pro-inflammatory-microglia-drive-escalated-alcohol-consumption-during",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-04T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.07.30.741570v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Despite growing evidence that neuroimmune dysfunction contributes to Alcohol Use Disorder (AUD) pathology, the underlying neuroinflammatory mechanisms that may promote alcohol consumption are not as clear. We recently report that specific knockdown of interferon regulatory factor 7 (IRF7) in the anterior insula (aIC) mitigates escalation in ethanol self-administration in rats. In addition, we…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}