{
  "id": 1633426,
  "title": "Genetic innovation in coronaviruses driven by a viral nuclease",
  "url": "https://urgent.news/2026/08/17/genetic-innovation-in-coronaviruses-driven-by-a-viral-nuclease",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-17T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.15.744938v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Genetic variation in viruses is well known to arise from polymerase-driven nucleotide misincorporation. However, insertion and deletion (indel) mutations that occur at lower, largely unknown, frequencies can underly more dramatic phenotypic changes that emerge when advantageous. Using a human coronavirus (HCoV-OC43) construct that reports rare indel mutations, we show that non-structural…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}