{
  "id": 1633421,
  "title": "Benchmarking fragmentation-derived artificial cfDNA reference standards",
  "url": "https://urgent.news/2026/08/17/benchmarking-fragmentation-derived-artificial-cfdna-reference",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-17T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.12.744389v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "An important step toward clinical implementation of (epi-)genomic assays on liquid biopsies is their validation on identical samples within and across laboratories. For these validation studies, there is a need for cell-free DNA (cfDNA) samples with defined tumor fractions and (epi-)genomic aberrations. However, the amount of circulating cfDNA isolated from patient samples is often limited,…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}