{
  "id": 16281725,
  "title": "Nonsense-mediated decay constrains transposable element-driven evolutionary innovation",
  "url": "https://urgent.news/2026/10/23/nonsense-mediated-decay-constrains-transposable-element-driven",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-23T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.22.760879v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Nonsense-mediated decay (NMD) degrades transcripts carrying premature termination codons, but its role in controlling transposable element-derived transcript diversity is unclear. We assembled an NMD-extended transcriptome (~217,000 transcripts, ~80% unannotated) from long-read RNA sequencing of cell lines after NMD inhibition. NMD-regulated transcripts were enriched in TE exonization,…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}