{
  "id": 16233265,
  "title": "SHROOM3 promotes leading-edge protrusion stability and Wnt/planar cell polarity-mediated migration in breast cancer cells",
  "url": "https://urgent.news/2026/10/23/shroom3-promotes-leading-edge-protrusion-stability-and-wnt-planar",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-23T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.22.761081v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Directional cell migration requires leading-edge protrusions to integrate actin polymerization, actomyosin contractility, and cell-matrix adhesion, but how polarity pathways spatially coordinate these processes remains incompletely understood. Wnt/planar cell polarity (Wnt/PCP) signaling promotes protrusive activity and migration in breast cancer cells. Here we identify the actin-associated…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}