{
  "id": 16179463,
  "title": "Expanding Therapeutic Target Space from Genes to Disease-Relevant Molecular Forms with Agent3Diso",
  "url": "https://urgent.news/2026/10/23/expanding-therapeutic-target-space-from-genes-to-disease-relevant",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-23T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.21.760710v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Therapeutic targets are commonly defined at the gene or canonical protein level, yet therapeutic effects are ultimately exerted through specific molecular states operating in specific biological contexts. Alternative splicing generates diverse RNA and translated protein forms whose functional consequences, disease relevance, and therapeutic vulnerabilities can differ substantially within the same…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}