{
  "id": 16113266,
  "title": "Multiparametric MRI and imaging transcriptomics reveal brain-wide changes in GD3 synthase deficiency",
  "url": "https://urgent.news/2026/10/22/multiparametric-mri-and-imaging-transcriptomics-reveal-brain-wide",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-22T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.16.759717v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Using an integrative imaging-transcriptomic approach that highlights the molecular complexity underlying neuroimaging phenotypes, we investigated a mouse model with disrupted ganglioside synthesis: the GD3 synthase-deficient mouse (St8sia1-null; GD3S KO). Gangliosides are membrane glycosphingolipids essential for brain development, neural plasticity and organisation of membrane lipid rafts. We…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}