{
  "id": 16075040,
  "title": "Multiple bottlenecks constrain presentation of Mycobacterium tuberculosis antigens on MHC class I",
  "url": "https://urgent.news/2026/10/22/multiple-bottlenecks-constrain-presentation-of-mycobacterium",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-22T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.16.759551v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "CD8+ T cell recognition of pathogen-derived peptides presented on major histocompatibility complex class I (MHC-I) contributes to protective immunity against intracellular pathogens like Mycobacterium tuberculosis (Mtb). However, it is currently difficult to predict which microbial antigens will be presented on MHC-I by infected cells. Prior studies have shown that proteins exported by Mtb's type…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}