{
  "id": 16051113,
  "title": "Supervised 3D Virtual Fluorescence and Pseudo-H&E Staining of Fresh Bulk Tissues via Multimodal qOBM and Fluorescence Microscopy",
  "url": "https://urgent.news/2026/10/22/supervised-3d-virtual-fluorescence-and-pseudo-h-e-staining-of-fresh",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-22T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.21.760751v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "We introduce a multimodal microscope that combines quantitative oblique back-illumination microscopy (qOBM) with wide-field epi-fluorescence deconvolution microscopy to acquire intrinsically co-registered phase and fluorescence volumes of fresh, bulk tissue. Using paired qOBM phase and DAPI fluorescence images of fresh ex vivo mouse brain tissue, we train a supervised conditional generative…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}