{
  "id": 16051098,
  "title": "AgamOBP4-targeted drug repurposing identifies novel mosquito repellent scaffolds",
  "url": "https://urgent.news/2026/10/22/agamobp4-targeted-drug-repurposing-identifies-novel-mosquito",
  "topic": "culture",
  "section": "Culture",
  "published": "2026-10-22T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.21.758783v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Odorant-binding proteins (OBPs) play central roles in insect chemoreception and represent attractive molecular targets for the discovery of novel behavior-modifying compounds. We report two crystal structures of Anopheles gambiae OBP4: one complexed with the fluorescent probe N-phenyl-1-naphthylamine and a second containing two indole molecules simultaneously bound within the ligand-binding…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}