{
  "id": 15955040,
  "title": "Feed-based delivery of plasmid DNA using milk-derived extracellular vesicle-polyethylenimine complexes enables hepatic transgene expression in goldfish",
  "url": "https://urgent.news/2026/10/21/feed-based-delivery-of-plasmid-dna-using-milk-derived-extracellular",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-21T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.20.760587v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Oral administration through feed offers a non-invasive, cost-effective, and scalable approach for gene delivery in aquaculture. However, gastrointestinal degradation and intestinal barriers severely limit the oral delivery of plasmid DNA (pDNA). In this study, we developed a ternary nanocarrier composed of bovine milk-derived extracellular vesicles (MEVs), polyethylenimine (PEI), and pDNA (MPPs)…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}