{
  "id": 15879012,
  "title": "IFNα differentially disrupts stimulus-secretion coupling in pancreatic alpha and beta cells",
  "url": "https://urgent.news/2026/10/21/ifn-differentially-disrupts-stimulus-secretion-coupling-in-pancreatic",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-21T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.20.760375v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Aims/hypothesis: IFN contributes to early islet inflammation and beta cell immunogenicity in type 1 diabetes, but its direct effects on endocrine cell function remain incompletely understood. We investigated whether acute IFN exposure disrupts glucose-regulated insulin and glucagon secretion and whether the underlying alterations in stimulus-secretion coupling differ between beta and alpha cells.…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}