{
  "id": 15827303,
  "title": "Mammalian cell-derived fatty acid biosynthesis derailment products are pro-inflammatory signalling molecules at the orphan receptor GPR84",
  "url": "https://urgent.news/2026/10/20/mammalian-cell-derived-fatty-acid-biosynthesis-derailment-products",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-20T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.14.759095v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "GPR84 is an orphan G protein coupled receptor (GPCR) implicated in inflammation. In 2006, decanoic acid was identified as a putative endogenous agonist, however subsequent work has found this to be implausible, leaving GPR84 officially classified as an orphan receptor. 6-Heptyl-4-hydroxy-2H-pyran-2-one (C7-alkylpyrone) was described as a GPR84 agonist in 2025. 6-Alkyl-4-hydroxy-2H-pyran-2-ones…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}