{
  "id": 15805067,
  "title": "Hyperactivation of β-catenin rewires mitochondrial fuel selection in liver cancer cells",
  "url": "https://urgent.news/2026/10/20/hyperactivation-of-catenin-rewires-mitochondrial-fuel-selection-in",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-20T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.18.759986v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Metabolic state is tightly linked to cell fate, and expression of the mitochondrial pyruvate carrier (MPC), which imports pyruvate into mitochondria, is a robust marker of it. The transcriptional regulators that set metabolic state, however, remain poorly defined. In the liver, {beta}-catenin is one of the determinants of metabolic zonation, and activating CTNNB1 mutations are frequent in…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}