{
  "id": 15751022,
  "title": "Experimental umbrella sampling of a rotary nanomachine",
  "url": "https://urgent.news/2026/10/20/experimental-umbrella-sampling-of-a-rotary-nanomachine",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-20T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.15.758702v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "The free-energy landscape of a molecular system, which describes its free energy as a function of a few collective coordinates, governs its dynamics and function, but is challenging to determine experimentally. In molecular simulations, enhanced-sampling methods such as umbrella sampling use bias potentials to access regions of this landscape that are rarely visited by equilibrium fluctuations.…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}