{
  "id": 15706231,
  "title": "Genomic foundation models do not yet boost common variant discovery beyond standard functional annotations",
  "url": "https://urgent.news/2026/10/19/genomic-foundation-models-do-not-yet-boost-common-variant-discovery",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-19T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.13.758880v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Genomic foundation models (GFMs) use large-scale AI to model genetic sequences and their influence on molecular phenotypes. While GFMs have shown promise in rare variant analysis, their utility for common variant discovery remains untested. Using the surrogate functional false discovery rate framework for functionally informed GWAS discovery, we compared standard functional annotations…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}