{
  "id": 15603902,
  "title": "Loss of the UFM-1 pathway enhances the ER Unfolded Protein Response under stress to improve proteostasis and organismal health in Caenorhabditis elegans",
  "url": "https://urgent.news/2026/10/19/loss-of-the-ufm-1-pathway-enhances-the-er-unfolded-protein-response",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-19T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.16.759640v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "The ubiquitin-like molecule (UBL) Ubiquitin-Fold Modifier 1 (UFM1) has emerged as an important regulator of protein quality control at the endoplasmic reticulum (ER). In humans, dysfunction of the UFM1 pathway is associated with neurodevelopmental diseases and cancer, however the physiological functions of the UFM-1 pathway are not well understood. Here, we used loss-of-function mutants in C.…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}