{
  "id": 15554207,
  "title": "Pleiotropy links host axes of defense against a pathogen",
  "url": "https://urgent.news/2026/10/18/pleiotropy-links-host-axes-of-defense-against-a-pathogen",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-18T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.12.758686v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Organisms face ubiquitous threats from pathogens, and in response hosts have evolved a cascade of defenses to avoid, resist, or tolerate infection. While these stepwise defenses may act independently, they can be pleiotropically linked via shared molecular mechanisms, regulation, and crosstalk. Here, we tested the extent to which pleiotropy shapes multiple axes of defense using knockouts of 16…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}