{
  "id": 151659,
  "title": "Methionine oxidation alters both helical assembly and disordered contacts in human TDP-43 C-terminal domain phase separation",
  "url": "https://urgent.news/2026/07/27/methionine-oxidation-alters-both-helical-assembly-and-disordered",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-07-27T07:00:00.000Z",
  "source": {
    "name": "PNAS",
    "slug": "pnas",
    "url": "https://www.pnas.org/doi/abs/10.1073/pnas.2537431123?af=R"
  },
  "original_language": "en",
  "account": null,
  "summary": "Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceHow chemically specific modifications tune interaction networks within disordered proteins and regulate condensate stability remains poorly understood. By integrating residue-resolved NMR spectroscopy with all-atom molecular simulations, we ...",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}