{
  "id": 15105502,
  "title": "Evaluating Nanopore read trimming and quality filtering in bacterial genomics",
  "url": "https://urgent.news/2026/10/16/evaluating-nanopore-read-trimming-and-quality-filtering-in-bacterial",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-16T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.12.758701v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Oxford Nanopore Technologies (ONT) sequencing is widely used in bacterial genomics, particularly for reference-based variant calling and de novo assembly. Both analyses routinely start with quality control (QC) preprocessing, but as ONT basecalling accuracy has improved, its necessity and downstream trade-offs remain poorly defined. We benchmarked 17 preprocessing combinations, built from three…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}