{
  "id": 1507918,
  "title": "Probing relaxed myosin states in hypertrophic cardiomyopathy by second harmonic-generation microscopy",
  "url": "https://urgent.news/2026/08/17/probing-relaxed-myosin-states-in-hypertrophic-cardiomyopathy-by",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-08-17T00:00:00.000Z",
  "source": {
    "name": "eLife",
    "slug": "elife",
    "url": "https://elifesciences.org/articles/107730"
  },
  "original_language": "en",
  "account": null,
  "summary": "This study explores the use of polarized second-harmonic generation (pSHG) to investigate myosin conformation in the relaxed state, differentiating between the actin-available, disordered (ON) state and the energy-conserving, ordered (OFF) state. By shifting the ON/OFF equilibrium using both physical and chemical manipulations, we demonstrate the sensitivity of pSHG in quantifying the ON/OFF…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}