{
  "id": 14961037,
  "title": "Nucleotide State Regulates Asymmetric Substrate-Binding Protein Docking in a Type II ABC Importer",
  "url": "https://urgent.news/2026/10/16/nucleotide-state-regulates-asymmetric-substrate-binding-protein",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-16T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.15.759412v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Type II ABC importers rely on substrate-binding proteins (SBP) to capture nutrients and deliver them to membrane-embedded transporters, but how ATP binding and hydrolysis regulate their interactions remains poorly understood. To address these questions, we determined structures of the Type II small-substrate molybdate importer MolBC-A from H. influenzae in distinct nucleotide-bound states,…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}