{
  "id": 14859380,
  "title": "Non-exonic read content reorganises lncRNA co-expression networks in renal and other cancers",
  "url": "https://urgent.news/2026/10/15/non-exonic-read-content-reorganises-lncrna-co-expression-networks-in",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-15T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.09.757827v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Co-expression networks are used to find prognostic lncRNA programmes, but lncRNA quantification depends on unprocessed RNA in the library. In renal cancer (1,062 patients), the leading lncRNA axis tracked the non-exonic (non-feature) read fraction, a routine alignment metric, at Spearman rho 0.90. Without adjustment, most of the lncRNA network merged into one module. Adjustment preserved…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}