{
  "id": 14610496,
  "title": "Resolution of chromosomal structural variation and vanA plasmid dynamics by nanopore-only sequencing across successive waves of a hospital outbreak of vancomycin-resistant Enterococcus faecium",
  "url": "https://urgent.news/2026/10/14/resolution-of-chromosomal-structural-variation-and-vana-plasmid",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-14T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.13.758403v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Allele-based typing may incompletely resolve vancomycin-resistant Enterococcus faecium (VREfm) outbreaks in clinical laboratories because it can miss chromosomal structural variation and resistance plasmid dynamics. We evaluated a nanopore-only sequencing workflow in 68 VREfm isolates collected during a single-hospital outbreak predominantly involving Bezdicek multilocus sequence typing (MLST)…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}