{
  "id": 14438703,
  "title": "Arrowhead’s brain-targeting RNA drug lowers Alzheimer’s protein in early study",
  "url": "https://urgent.news/2026/10/14/arrowheads-brain-targeting-rna-drug-lowers-alzheimers-protein-in",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-14T11:30:27.000Z",
  "source": {
    "name": "Endpoints News",
    "slug": "endpoints-news",
    "url": "https://endpoints.news/arrowheads-brain-targeting-rna-drug-lowers-alzheimers-protein-in-early-study/"
  },
  "original_language": "en",
  "account": null,
  "summary": "Arrowhead Pharmaceuticals has shown that a genetic medicine administered as a subcutaneous injection can seemingly travel into the brain and lower levels of tau, a protein implicated in Alzheimer’s disease. The company found that the ...",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 5,
    "also_reported_by": [
      {
        "outlet": "Science News",
        "title": "Scarred blood vessels may be one clue to APOE4’s Alzheimer’s risk",
        "url": "https://urgent.news/2026/10/12/scarred-blood-vessels-may-be-one-clue-to-apoe4s-alzheimers-risk",
        "published": "2026-10-12T16:00:00.000Z"
      },
      {
        "outlet": "Medical Xpress",
        "title": "Study offers new clues about how genetic risk for Alzheimer's affects brain immune cells",
        "url": "https://urgent.news/2026/10/12/study-offers-new-clues-about-how-genetic-risk-for-alzheimers-affects",
        "published": "2026-10-12T18:00:01.000Z"
      },
      {
        "outlet": "ETHealthworld",
        "title": "Early-onset Alzheimer's disease looks very different to late-onset version: Study",
        "url": "https://urgent.news/2026/10/13/early-onset-alzheimers-disease-looks-very-different-to-late-onset",
        "published": "2026-10-13T11:27:22.000Z"
      },
      {
        "outlet": "bioRxiv",
        "title": "Endothelial CD36 links arteriolar remodeling to metabolic and immune alterations in Alzheimer's disease",
        "url": "https://urgent.news/2026/10/14/endothelial-cd36-links-arteriolar-remodeling-to-metabolic-and-immune",
        "published": "2026-10-14T00:00:00.000Z"
      }
    ]
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}