{
  "id": 14405341,
  "title": "Nicotinic control of dopamine release shapes striatal output and engages adaptive action selection.",
  "url": "https://urgent.news/2026/10/14/nicotinic-control-of-dopamine-release-shapes-striatal-output-and",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-14T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.12.758519v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Acetylcholine and dopamine significantly modulate striatal circuits and are essential for reward learning and action selection. Cholinergic interneurons can locally trigger dopamine release through beta2-containing nicotinic acetylcholine receptors expressed on dopamine axons1-3. However, the causal contribution of this local cholinergic control of dopamine to behaviour and striatal output…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}