{
  "id": 13708619,
  "title": "Transcriptional perturbation effects remain structured beyond the leading global trend",
  "url": "https://urgent.news/2026/10/11/transcriptional-perturbation-effects-remain-structured-beyond-the",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-11T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.05.756839v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Prior work has described a global transcriptional response to gene perturbation, with many perturbations moving cells along a common direction. We find that perturbations contribute differently to this leading global trend and that substantial organization remains beyond it, including transferable perturbation-specific effects across datasets and a common hierarchy of responsive genes across…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}