{
  "id": 13626893,
  "title": "Repurposing clofarabine against enteric pathogens via metabolic starvation",
  "url": "https://urgent.news/2026/10/10/repurposing-clofarabine-against-enteric-pathogens-via-metabolic",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-10T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.09.757903v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Enteropathogenic and enterohaemorrhagic Escherichia coli (EPEC/EHEC) cause severe global diarrhoeal disease, exacerbated by rising antimicrobial resistance. Pathogenesis relies on \"attaching and effacing\" lesions, where bacteria generate actin pedestals to adhere, replicate, and destroy intestinal microvilli. To identify novel anti-virulence candidates targeting this process, we conducted a…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}