{
  "id": 13626890,
  "title": "EF-P-resolved ribosome stalling and collision trigger Rae1-mediated mRNA decay",
  "url": "https://urgent.news/2026/10/10/ef-p-resolved-ribosome-stalling-and-collision-trigger-rae1-mediated",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-10T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.09.757949v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Ribosome stalling compromises proteome integrity and cellular fitness, and requires efficient mechanisms to eliminate problematic mRNAs and rescue blocked ribosomes. We previously identified Rae1 as an endoribonuclease that cleaves mRNAs at the tail end of stalled ribosomes to promote mRNA degradation in Bacillus subtilis. Here, we show that Rae1 has a broader role in the quality control of mRNAs…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}