{
  "id": 13155711,
  "title": "Regulation of PL fimbriae (plf) and role of PlfB as a negative regulator during avian pathogenic Escherichia coli infection in turkeys",
  "url": "https://urgent.news/2026/10/09/regulation-of-pl-fimbriae-plf-and-role-of-plfb-as-a-negative",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-09T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.07.757495v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Little is currently known about the regulation of PL fimbriae produced by some pathogenic E. coli strains. We identified PlfB, a transcriptional regulator of the PapB family, as a negative regulator of PL fimbriae (Plf). Deletion of plfB significantly increased plfA transcription and Plf production. PlfB bound specifically to the plfA promoter region. Using a PplfA-lux reporter system, the…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}