{
  "id": 13132626,
  "title": "CLN6 is a glycerophosphoglycerol epimerase in bis(monoacylglycero)phosphate biosynthesis",
  "url": "https://urgent.news/2026/10/09/cln6-is-a-glycerophosphoglycerol-epimerase-in-bis-monoacylglycero",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-09T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.07.757350v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Lysosomal catabolism depends on bis(monoacylglycero)phosphate (BMP), a phospholipid with atypical S,S stereochemistry of unknown biosynthetic origin. CLN8 and CLN5 catalyze sequential acylation steps in BMP synthesis, and their loss of function causes Batten disease, a group of inherited neurodegenerative lysosomal storage disorders. Here we identify CLN6, a biochemically uncharacterized…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}