{
  "id": 13132618,
  "title": "The Red Blood Cell Surface Defines a Distinct Tumor DNA Compartment for Liquid Biopsy",
  "url": "https://urgent.news/2026/10/09/the-red-blood-cell-surface-defines-a-distinct-tumor-dna-compartment",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-09T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.07.755430v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Red blood cells (RBCs) modulate host inflammatory responses by scavenging mitochondrial and pathogen DNA. However, how RBC surface properties govern the capture of tumor-derived DNA remains poorly understood. We show that RBCs tether and retain tumor-derived DNA on their surface, forming a distinct circulating pool of RBC-bound tumor DNA (rtDNA). Desialylation increased DNA capture in a Toll-like…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}