{
  "id": 13109739,
  "title": "Combining AlphaFold 3 with microscale thermophoresis for aptamer optimisation",
  "url": "https://urgent.news/2026/10/09/combining-alphafold-3-with-microscale-thermophoresis-for-aptamer",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-09T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.08.757587v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Although use of AI-based tools has gained ground in molecular biology research, their reliability remains a matter of debate. Here, we combined AlphaFold 3 modelling with microscale thermophoresis to investigate the interactions between glucan-binding protein C and the biofilm-inhibiting aptamer and its five derivatives. Structural modelling identified a binding motif on the aptamer and suggested…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}