{
  "id": 12938200,
  "title": "A Bispecific Biologic That Robustly Reverses HIV-1 and SIV Latency",
  "url": "https://urgent.news/2026/10/08/a-bispecific-biologic-that-robustly-reverses-hiv-1-and-siv-latency",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-08T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.06.757104v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Antiretroviral therapy suppresses HIV-1 replication but cannot eliminate the latent viral reservoir persisting in memory CD4 T cells. Existing latency reversal candidates have yet to achieve robust viral reactivation at tolerable doses. We engineered T4IL15{triangleup}, a bispecific biologic that selectively delivers IL-15 signaling to memory CD4 T cells, with minimal off-target stimulation.…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}