{
  "id": 12656682,
  "title": "Immune aging speeds up around 40 and 60",
  "url": "https://urgent.news/2026/10/07/immune-aging-speeds-up-around-40-and-60",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-10-07T15:44:02.000Z",
  "source": {
    "name": "Futurity",
    "slug": "futurity",
    "url": "https://www.futurity.org/immune-aging-3348252/"
  },
  "original_language": "en",
  "account": null,
  "summary": "A new study from Duke-NUS Medical School has uncovered distinct waves of immune aging that occur around the ages of 40 and 60, with notable differences between men and women. The research, which analyzed 3.8 million immune cells from nearly 2,000 individuals, reveals that the immune system does not age at a steady pace, but experiences periods of accelerated aging. The fundamental machinery behind cell function, specifically genes responsible for RNA and protein synthesis, declines most at these two aging peak points. T cells, a type of white blood cell crucial for the immune system's response to germs, showed the most pronounced changes in gene activity around people's 40s and were the main drivers of a second wave of changes after age 60. The researchers found that the type of T cells that change profoundly at 40s and 60s is different between men and women, suggesting specialized roles at different stages of life. This discovery could help identify when and for whom interventions may have the greatest benefit and shed light on why some autoimmune conditions disproportionately affect women.",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}