{
  "id": 12656156,
  "title": "Genome accessibility reveals disease risk that gene expression misses",
  "url": "https://urgent.news/2026/10/07/genome-accessibility-reveals-disease-risk-that-gene-expression-misses",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-07T00:00:00.000Z",
  "source": {
    "name": "Nature",
    "slug": "nature",
    "url": "https://www.nature.com/articles/d41586-026-03072-5"
  },
  "original_language": "en",
  "account": null,
  "summary": "Nature, Published online: 07 October 2026; doi:10.1038/d41586-026-03072-5 Most disease-associated genetic alterations do not affect the genes themselves, but instead change how strongly they are expressed, often by modifying genome accessibility. Gene expression and accessibility have now been analysed simultaneously in 10 million immune cells from 1,108 people, linking disease-associated changes…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}