{
  "id": 12634092,
  "title": "Disentangling the Crabtree and Warburg effects across syngeneic non-tumor and tumor cells.",
  "url": "https://urgent.news/2026/10/07/disentangling-the-crabtree-and-warburg-effects-across-syngeneic-non",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-07T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.06.756891v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Oxidative phosphorylation (OxPhos) and substrate-level phosphorylation (SLP) are the primary biochemical mechanisms for ATP generation in mammalian cells. Increased dependency on SLP can arise from either transient (e.g., Crabtree effect) or chronic (e.g., Warburg effect) suppression of OxPhos. We evaluated the steady-state bioenergetics of quiescent and proliferating mouse cells matched in…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}