{
  "id": 12634078,
  "title": "Host Metabolic Reprogramming Defines Macrophage Antifungal Activity Against Cryptococcus neoformans",
  "url": "https://urgent.news/2026/10/07/host-metabolic-reprogramming-defines-macrophage-antifungal-activity",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-07T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.30.755789v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Innate immune cells, including macrophages and DCs, are critical for controlling infection by Cryptococcus neoformans. Although C. neoformans is phagocytosed equally by each pulmonary phagocyte subset, CD11b+ DCs support fungal growth, whereas Ly6c- monocyte-like macrophages are antifungal. The metabolic programs underlying these contrasting responses remain incompletely understood, but our…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}