{
  "id": 12427283,
  "title": "Axonal dysfunction precedes axonal degeneration in a mouse model of progressive parkinsonism",
  "url": "https://urgent.news/2026/10/06/axonal-dysfunction-precedes-axonal-degeneration-in-a-mouse-model-of",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-06T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.29.755486v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Axons of substantia nigra dopaminergic neurons \"die back\" in Parkinson's disease (PD), exhibiting early degeneration relative to cell bodies, a key feature also observed in PD models. A critical step towards understanding the process of axonal neurodegeneration is to determine the physiological properties of dopaminergic axons that are altered during the early stages of cellular dysfunction.…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}