{
  "id": 12202961,
  "title": "A new mouse model for a high-risk AMD variant, ARMS2A69S",
  "url": "https://urgent.news/2026/10/05/a-new-mouse-model-for-a-high-risk-amd-variant-arms2a69s",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-05T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.10.02.756275v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in older adults. The highest genetic risk for AMD maps to Chromosome 10q26. However, due to strong linkage disequilibrium between two genes, ARMS2 and HTRA1 located in this region, it has been difficult to determine whether one or both genes contribute to the AMD-disease risk. Functional studies of…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}