{
  "id": 1206548,
  "title": "Hepatic estrogen receptor α is required for stage specific coupling of liver metabolism and proliferation during pregnancy",
  "url": "https://urgent.news/2026/08/15/hepatic-estrogen-receptor-is-required-for-stage-specific-coupling-of",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-15T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.10.743939v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Background and Aims: Pregnancy requires dynamic, stage-specific adaptations in maternal liver metabolism and growth to sustain fetal development while preserving systemic homeostasis. Estrogen signaling, which significantly increases during pregnancy, is primarily mediated in hepatocytes by estrogen receptor (ER). Although hepatic ER regulates female liver metabolism under non-pregnant…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}