{
  "id": 11486831,
  "title": "Simulating Bead-Tethered Biomolecules: Force-Probe Coupled Steered Molecular Dynamics (fp-SMD) in Optical Tweezers Force Spectroscopy",
  "url": "https://urgent.news/2026/10/02/simulating-bead-tethered-biomolecules-force-probe-coupled-steered",
  "topic": "science",
  "section": "Science",
  "published": "2026-10-02T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.27.754810v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Interpreting single-molecule force spectroscopy (SMFS) data from optical tweezers with steered molecular dynamics (SMD) is hindered by a severe timescale mismatch: SMD trajectories span nanoseconds to microseconds, while SMFS experiments unfold over milliseconds to seconds, forcing SMD to pull six to nine orders of magnitude faster than experiment and systematically distorting rupture forces,…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}