{
  "id": 11037281,
  "title": "Serum 25(OH)D may serve as a biomarker of disease activity in IBD",
  "url": "https://urgent.news/2026/09/30/serum-25-oh-d-may-serve-as-a-biomarker-of-disease-activity-in-ibd",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-30T21:40:08.000Z",
  "source": {
    "name": "Medical Xpress",
    "slug": "medical-xpress",
    "url": "https://medicalxpress.com/news/2026-09-serum-25ohd-biomarker-disease-ibd.html"
  },
  "original_language": "en",
  "account": "In a study published in the Journal of Clinical Medicine, researchers from the Medical University of Lodz in Poland have found that serum 25-hydroxyvitamin D (25(OH)D) levels may serve as a biomarker for disease activity in patients with inflammatory bowel disease (IBD). The cross-sectional study, involving 129 IBD patients and 102 healthy controls, revealed that IBD patients had significantly lower 25(OH)D concentrations compared to the control group (25.5 ng/mL vs 28.8 ng/mL). The difference in 25(OH)D levels depended on the disease activity, with patients in remission having significantly higher vitamin D concentrations (28.9 ± 7.2 ng/mL) than those with active IBD (22.3 ± 6.1 ng/mL). This association was observed in both ulcerative colitis and Crohn disease. Furthermore, the study found a relationship between serum 25(OH)D concentrations, total dietary vitamin D intake, vitamin D supplementation, and disease remission. The authors suggest that serum 25(OH)D levels in IBD patients could serve as an additional, useful, and noninvasive marker of disease activity. Normalizing these levels may help reduce complications and improve remission rates, which is clinically significant. However, the researchers caution that vitamin D deficiency may be a consequence rather than a cause of active inflammation.",
  "summary": "For patients with inflammatory bowel disease (IBD), serum 25-hydroxyvitamin D (25[OH]D) may serve as a biomarker for disease activity, according to a study published online Sept. 10 in the Journal of Clinical Medicine.",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}